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Author (up) Deo, A.K. url  openurl
  Title Breast cancer stem-like cells and breast cancer therapy Type Journal Article
  Year Publication Breast cancer stem-like cells and breast cancer therapy Abbreviated Journal  
  Volume Issue 5 Pages 530-543  
  Keywords Breast cancer stem cells Signaling pathway Resistance  
  Abstract Until the early 1990s, human cancers were considered a morphologically heterogeneous population of cells. In 1997, Bonnet et al[1] demonstrated that a small population of leukemia cells was able to differentiate in vivo into leukemic blasts, indicating that the leukemic clone was organized as a hierarchy; this was subsequently denoted as cancer stem like cells (CSCs). CSCs are cancer cells that possess characteristics associated with normal stem cells and have the specific ability to give rise to all cell types found in a particular cancer. One reason for the failure of traditional anti tumor therapies might be their inability to eradicate CSCs. Therefore, therapies must identify and destroy CSCs in both primary and metastatic tumors.  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1674-0807 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number ref @ user @ ref4 Serial 100551  
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