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Author Deo, A.K.
Title Breast cancer stem-like cells and breast cancer therapy Type Journal Article
Year (down) Publication Breast cancer stem-like cells and breast cancer therapy Abbreviated Journal
Volume Issue 5 Pages 530-543
Keywords Breast cancer stem cells Signaling pathway Resistance
Abstract Until the early 1990s, human cancers were considered a morphologically heterogeneous population of cells. In 1997, Bonnet et al[1] demonstrated that a small population of leukemia cells was able to differentiate in vivo into leukemic blasts, indicating that the leukemic clone was organized as a hierarchy; this was subsequently denoted as cancer stem like cells (CSCs). CSCs are cancer cells that possess characteristics associated with normal stem cells and have the specific ability to give rise to all cell types found in a particular cancer. One reason for the failure of traditional anti tumor therapies might be their inability to eradicate CSCs. Therefore, therapies must identify and destroy CSCs in both primary and metastatic tumors.
Corporate Author Thesis
Publisher Place of Publication Editor
Language Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 1674-0807 ISBN Medium
Area Expedition Conference
Notes Approved no
Call Number ref @ user @ ref4 Serial 100551
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