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  Title [Neuromediators and neurotransmitters in the bone tissue remodeling] Type Journal Article
  Year 2012 Publication Aviakosmicheskaia i Ekologicheskaia Meditsina = Aerospace and Environmental Medicine Abbreviated Journal Aviakosm Ekolog Med  
  Volume 46 Issue 2 Pages 3-8  
  Keywords Bone Remodeling/*physiology; Bone Resorption/*pathology; Humans; Neurotransmitter Agents/*metabolism; Osteoblasts/metabolism; Osteoclasts/metabolism; Receptors, Neurotransmitter/metabolism; Space Flight; Sympathetic Nervous System/metabolism; Time Factors; Weightlessness  
  Abstract The review is devoted to the molecular mechanisms of bone resorption with recruitment of neuromediators and neurotransmitters executing the ladder processes of neuronal regulation and directly stimulating serotonergic, adrenergic, glutamatergic and GABA-ergic receptors of osteoblasts and osteoclasts. Microgravity-induced elevation of the sympathetic nervous system tone is considered a likely factor in the increase in bone resorption rate during long-duration space flight.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Russian Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0233-528X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:22953533 Approved no  
  Call Number refbase @ admin @ Serial 15518  
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