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Author (up) Shin, H.; Farnsworth, A.; Spratt, P.; Chang, V. url  openurl
  Title [Surgical treatment with aortic valve homograft harvested from heart transplant recipients or donors] Type Journal Article
  Year 1993 Publication [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai Abbreviated Journal Nihon Kyobu Geka Gakkai Zasshi  
  Volume 41 Issue 3 Pages 417-420  
  Keywords Adolescent; Adult; Aged; Aortic Valve/surgery/*transplantation; Female; *Heart Transplantation; Heart Valve Diseases/surgery; Humans; Male; Middle Aged; Tissue Donors; Tissue Survival; Transplantation, Homologous  
  Abstract From March 1988 to November 1991, 24 patients underwent aortic valve replacement or aortic root replacement with an aortic homograft harvested from a heart transplant recipient or donor that was not suitable for heart transplantation. Those patients were followed from 2 to 34 months (mean 12.6 months). The mean age was 44 years (range 19 to 77 years). The main lesion was aortic stenosis in 8 patients, aortic regurgitation in eight, mixed lesion in eight, annulo-aortic ectasia in two, active prosthetic valve endocarditis in two, and recurrent LVOTO in one. Cardiac status before operation was NYHA class II in one patient, III in nineteen, IV in four. Aortic valve replacement was performed in 17 patients, and aortic root replacement in seven. There was no early or late death. No structural deterioration was found. Surgical technical error resulted in moderate aortic regurgitation in one patient and mild paravalvular leak in another patient immediately after operation. All patients except one were not given anticoagulants postoperatively, but the entire group was free from thromboembolism. All patients returned to NYHA class I. Most homografts in this series were cryopreserved without antibiotic sterilization immediately after harvest, but homograft valve endocarditis did not occur. The results in this series suggested that homografts from heart transplant recipients or donors were encouraging, but more long-term follow-up was required to be determined whether homografts from heart transplant recipients without antibiotic sterilization were superior to homografts prepared in ordinary manner.  
  Address Department of Cardiothoracic Surgery, St. Vincent's Hospital, Sydney, Australia  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Japanese Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0369-4739 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:8478569 Approved no  
  Call Number refbase @ user @ Serial 21518  
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