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Author (up) Gou, Y.-Y.; Lin, S.; Que, D.E.; Tayo, L.L.; Lin, D.-Y.; Chen, K.-C.; Chen, F.-A.; Chiang, P.-C.; Wang, G.-S.; Hsu, Y.-C.; Chuang, K.P.; Chuang, C.-Y.; Tsou, T.-C.; Chao, H.-R. url  doi
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  Title Estrogenic effects in the influents and effluents of the drinking water treatment plants Type Journal Article
  Year 2016 Publication Environmental Science and Pollution Research International Abbreviated Journal Environ Sci Pollut Res Int  
  Volume Issue Pages  
  Keywords Di (2-ethylhexyl) phthalate (DEHP); Dibutyl phthalate (DBP); Drinking water; E-Screen; Estrogenic activity; T47D-KBluc assay  
  Abstract Estrogen-like endocrine disrupting compounds (EEDC) such as bisphenol A, nonylphenol, and phthalic acid esters are toxic compounds that may occur in both raw- and drinking water. The aim of this study was to combine chemical- and bioassay to evaluate the risk of EEDCs in the drinking water treatment plants (DWTPs). Fifty-six samples were collected from seven DWTPs located in northern-, central-, and southern Taiwan from 2011 to 2012 and subjected to chemical analyses and two bioassay methods for total estrogenic activity (E-Screen and T47D-KBluc assay). Among of the considered EEDCs, only dibutyl phthalate (DBP) and di (2-ethylhexyl) phthalate (DEHP) were detected in both drinking and raw water samples. DBP levels in drinking water ranged from <MDL to 0.840 mug/L and from <MDL to 0.760 mug/L in raw water. DEHP had higher detection rate (82.1 %) than other compounds and was present in both drinking water and raw water from all the DWTPs. The highest daily drinking water intake calculated for male and female were 0.0823 and 0.115 mug/kg per day. The two selected bioassays were conducted for the first batch of 56 samples and a detection rate of 23 % for estradiol equivalent (EEQ) lower than the LOQ to 1.3 and 15 % for EEQ lower than LOQ to 0.757 for the second 53 samples. Our results showed a good correlation between E-screen and chemical assay which indicates that a combination of both can be used in detecting EEDCs in environmental samples.  
  Address Emerging Compounds Research Center, Department of Environmental Science and Engineering, National Pingtung University of Science and Technology, Neipu, Pingtung County, 912, Taiwan. hrchao@mail.npust.edu.tw  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0944-1344 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:26791027 Approved no  
  Call Number ref @ user @ Serial 90796  
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