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Author (up) Abidi, M.Z.; Ledeboer, N.; Banerjee, A.; Hari, P.
Title Mycobacterium mucogenicum bacteremia in immune-compromised patients, 2008-2013 Type Journal Article
Year 2016 Publication Diagnostic Microbiology and Infectious Disease Abbreviated Journal Diagn Microbiol Infect Dis
Volume 85 Issue 2 Pages 182-185
Keywords Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents/therapeutic use; Bacteremia/drug therapy/*epidemiology; Humans; *Immunocompromised Host; Male; Middle Aged; Mycobacterium Infections, Nontuberculous/drug therapy/*epidemiology; Retrospective Studies; Risk Factors; Treatment Outcome; Young Adult; Bacteremia; Central venous catheter; Mycobacterium mucogenicum
Abstract Mycobacterium mucogenicum (MM) is a rapidly growing nontuberculous mycobacterium that may rarely cause bacteremia in immune-compromised hosts. All MM cases from 2008 to 2013 were analyzed across 4 risk groups: stem cell transplantation (SCT), hematologic malignancy, solid tumors, and others. Descriptive analysis was performed, as well as comparative analysis of neutropenic patients (absolute neutrophil count </=1000/muL) with nonneutropenic patients. Of 39 MM cases, 27 patients had undergone SCT. Neutropenia was present in 12 patients. There was a significant difference in the presence of fever at the time of MM bacteremia between neutropenic and nonneutropenic groups (92% versus 42%; P=0.005). Central venous catheter (CVC) was present in 33 cases. All patients were treated with >1 antibiotic. Most frequently used combination antibiotic regimen involved clarithromycin and amikacin. Median duration of antibiotic treatment was 42days. Bacteremia resolved in all cases with CVC removal and combination antibiotic treatment.
Address Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0732-8893 ISBN Medium
Area Expedition Conference
Notes PMID:27117516 Approved no
Call Number ref @ user @ Serial 99523
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