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Author Navarrete-Reyes, A.P.; Medina-Rimoldi, C.T.; Avila-Funes, J.A. url  doi
openurl 
  Title Correlates of subjective transportation deficiency among older adults attending outpatient clinics in a tertiary care hospital in Mexico City Type Journal Article
  Year 2017 Publication Geriatrics & Gerontology International Abbreviated Journal Geriatr Gerontol Int  
  Volume Issue Pages  
  Keywords Latin America; disability; mobility; older adults; transportation  
  Abstract AIM: Older adults frequently report problems of transportation. Little is known about the correlates of transportation deficiency in Latin America. Therefore, the aim of the present study was to determine the correlates of subjective transportation deficiency (STD) among community-dwelling older adults attending a tertiary care hospital in Mexico City. METHODS: Cross-sectional study of 228 participants aged >/=70 years being followed in any of the outpatient clinics of a tertiary care hospital in Mexico City. Data were obtained through a structured questionnaire. Univariate and multivariate logistic regression analyses were carried out in order to identify the correlates of STD. RESULTS: The mean age of the participants was 79.8 years (SD 6.4) and 67.1% were women. STD was present in 46% of participants. The multivariate logistic regression model showed that female sex, illiteracy, mobility disability and the use of an assistive walking device had an independent and statistically significant association with STD. CONCLUSIONS: Female sex, illiteracy, mobility disability and the use of an assistive walking device were independent correlates of STD in the present study. Identifying the frequency and correlates of transportation deficiency in vulnerable populations will allow for the identification and implementation of useful public policies, as well as for the optimization of prevention and treatment strategies in an attempt to preserve mobility and autonomy, especially in low- and middle-income countries where previous work on transportation deficiency is lacking. Geriatr Gerontol Int 2016; : -**.  
  Address (down) Research Center INSERM, Bordeaux, France  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1447-0594 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28190303 Approved no  
  Call Number ref @ user @ Serial 97448  
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Author Celiku, O.; Tandle, A.; Chung, J.-Y.; Hewitt, S.M.; Camphausen, K.; Shankavaram, U. url  doi
openurl 
  Title Computational analysis of the mesenchymal signature landscape in gliomas Type Journal Article
  Year 2017 Publication BMC Medical Genomics Abbreviated Journal BMC Med Genomics  
  Volume 10 Issue 1 Pages 13  
  Keywords Cd44; Computational modeling; Epithelial to mesenchymal transition; Glioma  
  Abstract BACKGROUND: Epithelial to mesenchymal transition, and mimicking processes, contribute to cancer invasion and metastasis, and are known to be responsible for resistance to various therapeutic agents in many cancers. While a number of studies have proposed molecular signatures that characterize the spectrum of such transition, more work is needed to understand how the mesenchymal signature (MS) is regulated in non-epithelial cancers like gliomas, to identify markers with the most prognostic significance, and potential for therapeutic targeting. RESULTS: Computational analysis of 275 glioma samples from “The Cancer Genome Atlas” was used to identify the regulatory changes between low grade gliomas with little expression of MS, and high grade glioblastomas with high expression of MS. TF (transcription factor)-gene regulatory networks were constructed for each of the cohorts, and 5 major pathways and 118 transcription factors were identified as involved in the differential regulation of the networks. The most significant pathway – Extracellular matrix organization – was further analyzed for prognostic relevance. A 20-gene signature was identified as having prognostic significance (HR (hazard ratio) 3.2, 95% CI (confidence interval) = 1.53-8.33), after controlling for known prognostic factors (age, and glioma grade). The signature's significance was validated in an independent data set. The putative stem cell marker CD44 was biologically validated in glioma cell lines and brain tissue samples. CONCLUSIONS: Our results suggest that the differences between low grade gliomas and high grade glioblastoma are associated with differential expression of the signature genes, raising the possibility that targeting these genes might prolong survival in glioma patients.  
  Address (down) Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, 10 Center Drive, Bldg. 10, Rm. B3B70, Bethesda, MD, 20892, USA. uma@mail.nih.gov  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1755-8794 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28279210 Approved no  
  Call Number ref @ user @ Serial 96602  
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Author Brinkmann, S. url  doi
openurl 
  Title “Fight the poisoners of the people!” The beginnings of food regulation in Sao Paulo and Rio de Janeiro, 1889-1930 Type Journal Article
  Year 2017 Publication Historia, Ciencias, Saude--Manguinhos Abbreviated Journal Hist Cienc Saude Manguinhos  
  Volume 24 Issue 2 Pages 313-331  
  Keywords  
  Abstract For urban Brazil, the First World War triggered a dramatic food crisis that brought with it a massive increase in falsified goods and led to an uproar among the general public. Critics targeted the health authorities, who were evidently unable to suppress these frauds. This text spans the First Republic period and shows that since its proclamation the issue of regulating the food trade was part of health policies, but implementation was repeatedly delayed because of other priorities. This situation only changed with the health reforms of the early 1920s, which allows us to identify the First World War food crisis as a decisive point for the Brazilian state to take responsibility in this area.  
  Address (down) Professor, Instituto de Estudios Europeos/Departamento de Ciencia Politica y Relaciones Internacionale/Universidad del Norte. Km. 5 via Puerto Colombia. 080001 – Barranquilla – Colombia. sbrinkmann@uninorte.edu.co  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title “Guerra aos envenenadores do povo!” Os inicios da regulacao de alimentos em Sao Paulo e no Rio de Janeiro, 1889-1930  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0104-5970 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28658421 Approved no  
  Call Number ref @ user @ Serial 98020  
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Author Barros, J.; Morales, S.; Echavarri, O.; Garcia, A.; Ortega, J.; Asahi, T.; Moya, C.; Fischman, R.; Maino, M.P.; Nunez, C. url  doi
openurl 
  Title Suicide detection in Chile: proposing a predictive model for suicide risk in a clinical sample of patients with mood disorders Type Journal Article
  Year 2017 Publication Revista Brasileira de Psiquiatria (Sao Paulo, Brazil : 1999) Abbreviated Journal Rev Bras Psiquiatr  
  Volume 39 Issue 1 Pages 1-11  
  Keywords Adolescent; Adult; Chile; Female; Humans; Male; Mental Disorders/complications/*psychology; Middle Aged; Models, Theoretical; Risk Factors; Sensitivity and Specificity; Socioeconomic Factors; Suicide/*prevention & control; Surveys and Questionnaires; Young Adult  
  Abstract Objective:: To analyze suicidal behavior and build a predictive model for suicide risk using data mining (DM) analysis. Methods:: A study of 707 Chilean mental health patients (with and without suicide risk) was carried out across three healthcare centers in the Metropolitan Region of Santiago, Chile. Three hundred forty-three variables were studied using five questionnaires. DM and machine-learning tools were used via the support vector machine technique. Results:: The model selected 22 variables that, depending on the circumstances in which they all occur, define whether a person belongs in a suicide risk zone (accuracy = 0.78, sensitivity = 0.77, and specificity = 0.79). Being in a suicide risk zone means patients are more vulnerable to suicide attempts or are thinking about suicide. The interrelationship between these variables is highly nonlinear, and it is interesting to note the particular ways in which they are configured for each case. The model shows that the variables of a suicide risk zone are related to individual unrest, personal satisfaction, and reasons for living, particularly those related to beliefs in one's own capacities and coping abilities. Conclusion:: These variables can be used to create an assessment tool and enables us to identify individual risk and protective factors. This may also contribute to therapeutic intervention by strengthening feelings of personal well-being and reasons for staying alive. Our results prompted the design of a new clinical tool, which is fast and easy to use and aids in evaluating the trajectory of suicide risk at a given moment.  
  Address (down) Private practice  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1516-4446 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27783715 Approved no  
  Call Number ref @ user @ Serial 97654  
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Author Moimaz, S.A.S.; Rocha, N.B.; Garbin, C.A.S.; Rovida, T.A.; Saliba, N.A. url  doi
openurl 
  Title Factors affecting intention to breastfeed of a group of Brazilian childbearing women Type Journal Article
  Year 2017 Publication Women and Birth : Journal of the Australian College of Midwives Abbreviated Journal Women Birth  
  Volume 30 Issue 2 Pages e119-e124  
  Keywords Adult; Age Factors; Brazil; Breast Feeding/*psychology; Female; Humans; Mothers/*psychology; Pregnancy; Retrospective Studies; Socioeconomic Factors; Young Adult; Brazil; Breastfeeding; Breastfeeding difficulties; Breastfeeding initiation; Pregnancy  
  Abstract BACKGROUND: Knowing the intention of mothers is important to plan actions to improve exclusive breastfeeding rates. AIM: The objective of this retrospective study was to verify the intention to breastfeed and the intended breastfeeding duration of a group of women participating in a public prenatal dental care program in the city of Aracatuba, Brazil. METHODS: The records of 933 childbearing women were analyzed and their intention to breastfeed and intended breastfeeding duration were associated to women's age, ethnicity, marital status, education, employment, number of gestations, previous breastfeeding experience, previous breastfeeding guidance, presence of complications during pregnancy, and systemic diseases. Data were inserted into Epi Info 2000 and analyzed with Biostat, at a 5% level of significance, and confidence interval of 95%. FINDINGS: Participants mean age was 26.1+/-5.9years. The majority of women (96.5%) declared their intention to breastfeed their babies. The main variables to affect the intention to breastfeed were the number of gestations (p=0.001), previous breastfeeding experience (p=0.03), and previous breastfeeding guidance (p=0.01). Intended breastfeeding duration was significantly affected by women's age (p=0.04), employment (0.02), the number of gestations (p=0.001), and previous breastfeeding experience (p=0.04). CONCLUSIONS: Previous positive breastfeeding experience and guidance during prenatal examinations positively affected women's intention to breastfeed; while older, unemployed women in their second or more gestation and previous breastfeeding experience intended to breastfeed their children for longer periods of time.  
  Address (down) Preventive and Social Dentistry Department, School of Dentistry, Sao Paulo State University (UNESP), Aracatuba, Brazil. Electronic address: nemre@foa.unesp.br  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1871-5192 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:27840072 Approved no  
  Call Number ref @ user @ Serial 97339  
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