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Author (up) Blitchtein-Winicki, D.; Zevallos, K.; Samolski, M.R.; Requena, D.; Velarde, C.; Briceno, P.; Piazza, M.; Ybarra, M.L. url  doi
openurl 
  Title Feasibility and Acceptability of a Text Message-Based Smoking Cessation Program for Young Adults in Lima, Peru: Pilot Study Type Journal Article
  Year 2017 Publication JMIR MHealth and UHealth Abbreviated Journal JMIR Mhealth Uhealth  
  Volume 5 Issue 8 Pages e116  
  Keywords Pilot Projects, Text Messaging, Smoking Cessation, Young Adult, Cognitive Therapy, Feasibility Studies, Latinos  
  Abstract BACKGROUND: In Peru's urban communities, tobacco smoking generally starts during adolescence and smoking prevalence is highest among young adults. Each year, many attempt to quit, but access to smoking cessation programs is limited. Evidence-based text messaging smoking cessation programs are an alternative that has been successfully implemented in high-income countries, but not yet in middle- and low-income countries with limited tobacco control policies. OBJECTIVE: The objective was to assess the feasibility and acceptability of an short message service (SMS) text message-based cognitive behavioral smoking cessation program for young adults in Lima, Peru. METHODS: Recruitment included using flyers and social media ads to direct young adults interested in quitting smoking to a website where interested participants completed a Google Drive survey. Inclusion criteria were being between ages 18 and 25 years, smoking at least four cigarettes per day at least 6 days per week, willing to quit in the next 30 days, owning a mobile phone, using SMS text messaging at least once in past year, and residing in Lima. Participants joined one of three phases: (1) focus groups and in-depth interviews whose feedback was used to develop the SMS text messages, (2) validating the SMS text messages, and (3) a pilot of the SMS text message-based smoking cessation program to test its feasibility and acceptability among young adults in Lima. The outcome measures included adherence to the SMS text message-based program, acceptability of content, and smoking abstinence self-report on days 2, 7, and 30 after quitting. RESULTS: Of 639 participants who completed initial online surveys, 42 met the inclusion criteria and 35 agreed to participate (focus groups and interviews: n=12; validate SMS text messages: n=8; program pilot: n=15). Common quit practices and beliefs emerged from participants in the focus groups and interviews informed the content, tone, and delivery schedule of the messages used in the SMS text message smoking cessation program. A small randomized controlled pilot trial was performed to test the program's feasibility and acceptability; nine smokers were assigned to the SMS text message smoking cessation program and six to a SMS text message nutrition program. Participant retention was high: 93% (14/15) remained until day 30 after quit day. In all, 56% of participants (5/9) in the SMS text message smoking cessation program reported remaining smoke-free until day 30 after quit day and 17% of participants (1/6) in the SMS text message nutrition program reported remaining smoke-free during the entire program. The 14 participants who completed the pilot reported that they received valuable health information and approved the delivery schedule of the SMS text messages. CONCLUSIONS: This study provides initial evidence that a SMS text message smoking cessation program is feasible and acceptable for young adults residing in Lima.  
  Address Center for Innovative Public Health Research, San Clemente, CA, United States  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 2291-5222 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28778850 Approved no  
  Call Number ref @ user @ Serial 98009  
Permanent link to this record
 

 
Author (up) Blot, S.; Bauer, G.; Fraser, M.; Nleya, M.; Wadham, M. url  doi
openurl 
  Title AIDS Service Organization Access Among African, Caribbean and Other Black Residents of an Average Canadian City Type Journal Article
  Year 2017 Publication Journal of Immigrant and Minority Health Abbreviated Journal J Immigr Minor Health  
  Volume 19 Issue 4 Pages 851-860  
  Keywords African; Black people; Caribbean; Hiv/Aids; Health disparities; Health services research; Immigrant health; Minority health  
  Abstract Due to heightened vulnerability to HIV/AIDS, African, Caribbean and Black (ACB) communities are priority groups for prevention and intervention services in Canada. However, it is not clear which factors may affect ACB communities' access to these services. We evaluated access to the local AIDS service organization (ASO) in Middlesex-London by using data from the Black, African and Caribbean Canadian Health Study. Modified Poisson regression was used to obtain prevalence risk ratios for factors associated with three measures of access: familiarity with the ASO, willingness to access, and realized access. In adjusted analyses, older ACB community members were more likely to be familiar with the ASO, willing to access it, and have actually gone there. Canadian-born participants were less likely to have been to the ASO than recent immigrants. These results have implications for reaching specific segments of ACB communities for HIV/AIDS-related services in Canada.  
  Address Women and HIV/AIDS Initiative, Toronto, ON, Canada  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1557-1912 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:26895153 Approved no  
  Call Number ref @ user @ Serial 97194  
Permanent link to this record
 

 
Author (up) Blot, S.; Bauer, G.; Fraser, M.; Nleya, M.; Wadham, M. url  doi
openurl 
  Title AIDS Service Organization Access Among African, Caribbean and Other Black Residents of an Average Canadian City Type Journal Article
  Year 2017 Publication Journal of Immigrant and Minority Health Abbreviated Journal J Immigr Minor Health  
  Volume 19 Issue 4 Pages 851-860  
  Keywords African; Black people; Caribbean; Hiv/Aids; Health disparities; Health services research; Immigrant health; Minority health  
  Abstract Due to heightened vulnerability to HIV/AIDS, African, Caribbean and Black (ACB) communities are priority groups for prevention and intervention services in Canada. However, it is not clear which factors may affect ACB communities' access to these services. We evaluated access to the local AIDS service organization (ASO) in Middlesex-London by using data from the Black, African and Caribbean Canadian Health Study. Modified Poisson regression was used to obtain prevalence risk ratios for factors associated with three measures of access: familiarity with the ASO, willingness to access, and realized access. In adjusted analyses, older ACB community members were more likely to be familiar with the ASO, willing to access it, and have actually gone there. Canadian-born participants were less likely to have been to the ASO than recent immigrants. These results have implications for reaching specific segments of ACB communities for HIV/AIDS-related services in Canada.  
  Address Women and HIV/AIDS Initiative, Toronto, ON, Canada  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1557-1912 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:26895153 Approved no  
  Call Number ref @ user @ Serial 97682  
Permanent link to this record
 

 
Author (up) Brinkmann, S. url  doi
openurl 
  Title “Fight the poisoners of the people!” The beginnings of food regulation in Sao Paulo and Rio de Janeiro, 1889-1930 Type Journal Article
  Year 2017 Publication Historia, Ciencias, Saude--Manguinhos Abbreviated Journal Hist Cienc Saude Manguinhos  
  Volume 24 Issue 2 Pages 313-331  
  Keywords  
  Abstract For urban Brazil, the First World War triggered a dramatic food crisis that brought with it a massive increase in falsified goods and led to an uproar among the general public. Critics targeted the health authorities, who were evidently unable to suppress these frauds. This text spans the First Republic period and shows that since its proclamation the issue of regulating the food trade was part of health policies, but implementation was repeatedly delayed because of other priorities. This situation only changed with the health reforms of the early 1920s, which allows us to identify the First World War food crisis as a decisive point for the Brazilian state to take responsibility in this area.  
  Address Professor, Instituto de Estudios Europeos/Departamento de Ciencia Politica y Relaciones Internacionale/Universidad del Norte. Km. 5 via Puerto Colombia. 080001 – Barranquilla – Colombia. sbrinkmann@uninorte.edu.co  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title “Guerra aos envenenadores do povo!” Os inicios da regulacao de alimentos em Sao Paulo e no Rio de Janeiro, 1889-1930  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0104-5970 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28658421 Approved no  
  Call Number ref @ user @ Serial 98020  
Permanent link to this record
 

 
Author (up) Brodie, S.; Lee, H.K.; Jiang, W.; Cazacu, S.; Xiang, C.; Poisson, L.M.; Datta, I.; Kalkanis, S.; Ginsberg, D.; Brodie, C. url  doi
openurl 
  Title The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Type Journal Article
  Year 2017 Publication Oncotarget Abbreviated Journal Oncotarget  
  Volume 8 Issue 19 Pages 31785-31801  
  Keywords Talnec2; glioblastoma; glioma stem cells; long non-cording RNAs; mesenchymal transformation  
  Abstract Despite advances in novel therapeutic approaches for the treatment of glioblastoma (GBM), the median survival of 12-14 months has not changed significantly. Therefore, there is an imperative need to identify molecular mechanisms that play a role in patient survival. Here, we analyzed the expression and functions of a novel lncRNA, TALNEC2 that was identified using RNA seq of E2F1-regulated lncRNAs. TALNEC2 was localized to the cytosol and its expression was E2F1-regulated and cell-cycle dependent. TALNEC2 was highly expressed in GBM with poor prognosis, in GBM specimens derived from short-term survivors and in glioma cells and glioma stem cells (GSCs). Silencing of TALNEC2 inhibited cell proliferation and arrested the cells in the G1\S phase of the cell cycle in various cancer cell lines. In addition, silencing of TALNEC2 decreased the self-renewal and mesenchymal transformation of GSCs, increased sensitivity of these cells to radiation and prolonged survival of mice bearing GSC-derived xenografts. Using miRNA array analysis, we identified specific miRNAs that were altered in the silenced cells that were associated with cell-cycle progression, proliferation and mesenchymal transformation. Two of the downregulated miRNAs, miR-21 and miR-191, mediated some of TALNEC2 effects on the stemness and mesenchymal transformation of GSCs. In conclusion, we identified a novel E2F1-regulated lncRNA that is highly expressed in GBM and in tumors from patients of short-term survival. The expression of TALNEC2 is associated with the increased tumorigenic potential of GSCs and their resistance to radiation. We conclude that TALNEC2 is an attractive therapeutic target for the treatment of GBM.  
  Address Davidson Laboratory of Cell Signaling and Tumorigenesis, Hermelin Brain Tumor Center, Department of Neurosurgery, Detroit, MI, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1949-2553 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28423669 Approved no  
  Call Number ref @ user @ Serial 96594  
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