| Records |
| Author |
Lee, J.W.; Lim, D.H.; Sung, K.W.; Lee, H.J.; Yi, E.S.; Yoo, K.H.; Koo, H.H.; Suh, Y.L.; Shin, H.J. |
| Title |
Tandem High-Dose Chemotherapy and Autologous Stem Cell Transplantation for High-Grade Gliomas in Children and Adolescents |
Type |
Journal Article |
| Year |
2017 |
Publication |
Journal of Korean Medical Science |
Abbreviated Journal |
J Korean Med Sci |
Volume  |
32 |
Issue |
2 |
Pages |
195-203 |
| Keywords |
Adolescent; Antineoplastic Combined Chemotherapy Protocols/*therapeutic use; Brain Neoplasms/*drug therapy/mortality/therapy; Carboplatin/administration & dosage; Child; Child, Preschool; Etoposide/administration & dosage; Female; Glioma/*drug therapy/mortality/therapy; Humans; Male; Neoplasm Grading; Remission Induction; Retrospective Studies; Stem Cell Transplantation; Survival Rate; Thiotepa/administration & dosage; Transplantation, Autologous; Treatment Outcome; *Autologous Stem Cell Transplantation; *Brain Tumor; *Children; *High-dose Chemotherapy; *High-grade Glioma |
| Abstract |
With the aim to investigate the outcome of tandem high-dose chemotherapy and autologous stem cell transplantation (HDCT/auto-SCT) for high-grade gliomas (HGGs), we retrospectively reviewed the medical records of 30 patients with HGGs (16 glioblastomas, 7 anaplastic astrocytomas, and 7 other HGGs) between 2006 and 2015. Gross or near total resection was possible in 11 patients. Front-line treatment after surgery was radiotherapy (RT) in 14 patients and chemotherapy in the remaining 16 patients including 3 patients less than 3 years of age. Eight of 12 patients who remained progression free and 5 of the remaining 18 patients who experienced progression during induction treatment underwent the first HDCT/auto-SCT with carboplatin + thiotepa + etoposide (CTE) regimen and 11 of them proceeded to the second HDCT/auto-SCT with cyclophosphamide + melphalan (CyM) regimen. One patient died from hepatic veno-occlusive disease (VOD) during the second HDCT/auto-SCT; otherwise, toxicities were manageable. Four patients in complete response (CR) and 3 of 7 patients in partial response (PR) or second PR at the first HDCT/auto-SCT remained event free: however, 2 patients with progressive tumor experienced progression again. The probabilities of 3-year overall survival (OS) after the first HDCT/auto-SCT in 11 patients in CR, PR, or second PR was 58.2% +/- 16.9%. Tumor status at the first HDCT/auto-SCT was the only significant factor for outcome after HDCT/auto-SCT. There was no difference in survival between glioblastoma and other HGGs. This study suggests that the outcome of HGGs in children and adolescents after HDCT/auto-SCT is encouraging if the patient could achieve CR or PR before HDCT/auto-SCT. |
| Address |
Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. shinhj@skku.edu |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1011-8934 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:28049229 |
Approved |
no |
| Call Number |
ref @ user @ |
Serial |
96614 |
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| Author |
Girardi, S.N.; Carvalho, C.L.; Maas, L.W.D.; Araujo, J.F.; Massote, A.W.; Stralen, A.C. de S. van; Souza, O.A. de |
| Title |
[Preferences for work in primary care among medical students in Minas Gerais State, Brazil: evidence from a discrete choice experiment] |
Type |
Journal Article |
| Year |
2017 |
Publication |
Cadernos de Saude Publica |
Abbreviated Journal |
Cad Saude Publica |
| Volume |
33 |
Issue |
8 |
Pages |
e00075316 |
| Keywords |
Brazil; *Career Choice; Choice Behavior; Female; Humans; Income; Male; *Primary Health Care; *Professional Practice Location; Sex Factors; *Students, Medical; Surveys and Questionnaires |
| Abstract |
This article presents the results of a discrete choice experiment (DCE) conducted in 2012 with 277 final-year medical students from Minas Gerais State, Brazil. The experiment tested students' preferences concerning future work as physicians in primary health care, based on hypothetical job scenarios aimed at measuring the likelihood of placement in areas with a shortage of doctors. Application of DCE involved (i) a qualitative stage to define the attributes and their respective levels to comprise the job scenarios, (ii) construction and application of the instrument, and (iii) analysis with application of multinomial logit with conditional probability to estimate the weight of attributes and to construct scenarios for choice probability. The results indicate that the job attribute that most impacted students' choice was location, followed by job conditions, pay, access to medical residency, type of employment relationship, and workload. Students from private medical schools, with higher family income, and females were generally more likely to resist job assignments in unsafe urban areas and remote areas of the countryside. The job scenarios that proved most plausible in terms of public intervention were those that combined middle-level wages, good working conditions, and 10 to 20 bonus points on medical residency exams. |
| Address |
Departamento de Matematica, Universidade Estadual do Centro-Oeste, Guarapuava, Brasil |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
Portuguese |
Summary Language |
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Original Title |
Preferencias para o trabalho na atencao primaria por estudantes de medicina em Minas Gerais, Brasil: evidencias de um experimento de preferencia declarada |
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Series Title |
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Abbreviated Series Title |
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Edition |
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| ISSN |
0102-311X |
ISBN |
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Expedition |
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Conference |
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| Notes |
PMID:28832780 |
Approved |
no |
| Call Number |
ref @ user @ |
Serial |
97630 |
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| Author |
Mello, A. de C.; Carvalho, M.S.; Alves, L.C.; Gomes, V.P.; Engstrom, E.M. |
| Title |
[Food consumption and anthropometry related to the frailty syndrome in low-income community-living elderly in a large city] |
Type |
Journal Article |
| Year |
2017 |
Publication |
Cadernos de Saude Publica |
Abbreviated Journal |
Cad Saude Publica |
| Volume |
33 |
Issue |
8 |
Pages |
e00188815 |
| Keywords |
Aged; Aged, 80 and over; *Anthropometry; Brazil; Cross-Sectional Studies; Female; *Food; Frail Elderly/*statistics & numerical data; Geriatric Assessment; Humans; Male; Middle Aged; Nutrition Assessment; Nutrition Surveys; Socioeconomic Factors |
| Abstract |
The aim of this study was to describe anthropometric and food intake data related to the frailty syndrome in the elderly. This was a cross-sectional study in individuals >/= 60 years of age in a household survey in the Manguinhos neighborhood of Rio de Janeiro, Brazil (n = 137). Frailty syndrome was diagnosed according to Fried et al., anthropometric measures were taken, and a food frequency questionnaire was applied and the results compared to Brazilian Ministry of Health guidelines. In the pre-frail and frail groups, body mass index and measures of central adiposity showed higher levels, while lean muscle parameters showed lower values, proportional to the syndrome's gradation. Frail elderly consumed higher amounts of grains and lower amounts of beans and fruit; pre-frail elderly consumed more vegetables, dairy products, and high-sugar and high-fat foods; the two groups consumed similar amounts of meat. Thus, diagnosis of the syndrome, anthropometric evaluation, and dietary assessment should be included in health policies for the elderly, since they assist in early identification of risk and favor interventions for disease prevention and health and nutritional promotion. |
| Address |
Escola Nacional de Saude Publica Sergio Arouca, Fundacao Oswaldo Cruz, Rio de Janeiro, Brasil |
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Place of Publication |
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| Language |
Portuguese |
Summary Language |
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Original Title |
Consumo alimentar e antropometria relacionados a sindrome de fragilidade em idosos residentes em comunidade de baixa renda de um grande centro urbano |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0102-311X |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:28832786 |
Approved |
no |
| Call Number |
ref @ user @ |
Serial |
98007 |
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| Author |
Cruz, M.F. da; Ramires, V.V.; Wendt, A.; Mielke, G.I.; Martinez-Mesa, J.; Wehrmeister, F.C. |
| Title |
[Simultaneity of risk factors for chronic non-communicable diseases in the elderly in Pelotas, Rio Grande do Sul State, Brazil] |
Type |
Journal Article |
| Year |
2017 |
Publication |
Cadernos de Saude Publica |
Abbreviated Journal |
Cad Saude Publica |
| Volume |
33 |
Issue |
2 |
Pages |
e00021916 |
| Keywords |
Aged; Aged, 80 and over; Alcoholism/epidemiology; Brazil/epidemiology; Chronic Disease/*epidemiology; Cluster Analysis; Cross-Sectional Studies; Exercise; Female; Humans; Male; Middle Aged; Obesity/epidemiology; Prevalence; Risk Factors; Sex Factors; Smoking/epidemiology; Socioeconomic Factors |
| Abstract |
This study aimed to describe the simultaneity of risk factors for chronic non-communicable diseases among the elderly (</= 60 years) in a city in Southern Brazil. This was a cross-sectional, population-based study of 1,451 elderly in 2013. Cluster analysis was applied to selected risk factors (smoking, alcohol consumption, excess weight, and physical inactivity). Logistic regression was used to assess the association between simultaneity of risk factors and socio-demographic variables. The most frequent cluster in men (18.1%) and women (30.7%) was physical inactivity + excess weight. The cluster alcohol consumption + excess weight exceeded the expected level in men (O/E = 1.27; 95%CI: 1.01; 1.59) and women (O/E = 1.72; 95%CI: 1.35; 2.20). The presence of two or more risk factors in the elderly population (88.1%) points to the need for specific interventions for this population to fight risk factors simultaneously rather than separately. |
| Address |
Universidade Federal de Pelotas, Pelotas, Brasil |
| Corporate Author |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
Portuguese |
Summary Language |
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Original Title |
Simultaneidade de fatores de risco para doencas cronicas nao transmissiveis entre idosos da zona urbana de Pelotas, Rio Grande do Sul, Brasil |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0102-311X |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:28403276 |
Approved |
no |
| Call Number |
ref @ user @ |
Serial |
98024 |
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| Author |
Gomes, F. da S.; Silva, G.A.E.; Castro, I.R.R. de |
| Title |
[Household purchase of sodas and cookies reduces the effect of an intervention to promote the consumption of fruits and vegetables] |
Type |
Journal Article |
| Year |
2017 |
Publication |
Cadernos de Saude Publica |
Abbreviated Journal |
Cad Saude Publica |
| Volume |
33 |
Issue |
3 |
Pages |
e00023316 |
| Keywords |
Beverages/*statistics & numerical data; Brazil; Candy/*statistics & numerical data; Diet Surveys; *Feeding Behavior; Female; *Fruit; *Health Promotion; Humans; Male; Socioeconomic Factors; *Vegetables |
| Abstract |
This study examines the influence of increasing household availability of sodas and cookies on the effects of an intervention to promote the consumption of fruits and vegetables. The study analyzed data from 70 families living in low-income communities in the city of Rio de Janeiro, Brazil, selected in a stratified probabilistic sample, and who completed a 30-day food record before and after the intervention. The intervention contributed to a significant increase in the household availability of fruit and vegetables (+2.7 p.p.; 95%CI: 1.5; 4.0), contrary to the trend towards stagnation of such availability in the general population in Brazil. Meanwhile, the purchase of sodas and cookies, which was not the intervention's target, mirrored the upward trend in the consumption of these products (+5.8 p.p.; 95%CI: 3.3; 8.4). Families that increased their purchase of sodas and cookies showed lower increases, or even decreases, in the purchase of fruits and vegetables (p < 0.05), and had nearly fourfold lower odds of experiencing any increase in the household availability of fruits and vegetables. |
| Address |
Instituto de Nutricao, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brasil |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
Portuguese |
Summary Language |
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Original Title |
Aquisicao domiciliar de refrigerantes e de biscoitos reduz o efeito de uma intervencao de promocao de frutas e hortalicas |
| Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0102-311X |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:28380139 |
Approved |
no |
| Call Number |
ref @ user @ |
Serial |
98025 |
| Permanent link to this record |
